CENTRAL PONTINE MYELINOLYSIS

CT scan - non enhanced - hypoattenuation
MRI - T1- low signal intensity
           T2 -high signal
          Post contrast T1- Non enhancing

Pathology :
Non inflammatory demyelination involving the oligodendroglial cells in pons , basal ganglia etc

Seen commonly in alcoholics with metabolic defects who were overzealously treated with electrolyte infusion

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