http://learningradiology.com/archives2011/COW%20441-Pheochromocytoma/pheocorrect.htm
Imaging Findings
- Over 90% located in adrenal, 98% in abdomen
- Imaging studies are performed after the diagnosis is made on a biochemical basis
- MRI is the preferred study
- Hyperintense on T2-weighted images
- No contrast required
- CT scanning
- Most have a pre-contrast attenuation >10 HU
- Contrast was thought to add the risk of inducing hypertensive crisis but no increased risk has been shown with low-osmolar contrast
- Most lesions vigorously contrast-enhance (>80 HU) and have less than 60% washout of contrast on delayed images
- PET scans have also proved helpful in finding the lesions
Differential Diagnosis
- Adrenal adenomas
- Adrenal carcinomas
- Adrenal metastases
Associations
- Von-Hippel Lindau disease
- Neurofibromatosis
- Multiple endocrine neoplasia (MEN) 2A (Sipple syndrome) and 2B
- Tuberous sclerosis
- Sturge-Weber syndrome
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